Cecal Ligation and Puncture (CLP) was used in [1]

“We performed CLP in BALB/c mice, the most relevant animal model for clinical sepsis.” How is this performed in detail, what do the clinical scores mean- how do they relate to human disease, and what makes BALB/c the “most relevant animal model”?

For a detailed report by A. Bhattacharya,(requires access to TMA google group) click here