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Diphtheria Toxin Receptor -Transgenic mice

How does the CD11c DTR system work? Is this a knock-in or is it a promoter/cDNA construct? How efficient is the deletion? How specific is the deletion for CD11c+ cells?


This was used by Divangahi et al. Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis.Nature immunology, Vol. 11, No. 8. (11 August 2010), pp. 751-758

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